The relationship between serum level of 25- hydroxy vitamin D with anthropometric indices and some biochemical parameters in obese women

Background : Some studies have shown that the serum concentration of 25- hydroxy vitamin D which is represent the status of body vitamin D, has a diverse relationship with obesity status, and the risk of obesity decreases in people with high level of 25- hydroxy vitamin D. The aim of this study is to investigate the correlation between the serum level of 25- hydroxy vitamin D and anthropometric indices, glucose, lipid profile, serum insulin, and insulin resistance in obese women. Materials and Methods: This study was carried out on 43 obese women and 43 healthy women with normal weight as a control group, aged 20-50. They were matched for age and physical activity. For each participant, a 3-day 24-hours food recall was filled. Moreover, fasting blood sampling was taken to measure blood levels of fasting blood glucose, 25- hydroxy vitamin D, lipid profile and serum insulin. Results: The mean level of serum 25- hydroxy vitamin D, insulin and also insulin resistance based on IR-HOMA index in the group of obesity and control were 28.05 ± 16.66 versus 25.72 ± 14.08 (P=0.48 ) , 25.97 ± 7.53 versus 25.93 ± 9.32 (P=0.98 ) , and 6.39 ± 2.6 versus 5.83 ± 2.5 (P=0.30) respectively. Between the anthropometric indices, 25- hydroxy vitamin D had a significant relationship only with body weight in obese group (p=0.033, r= 0.326 ). No significant relationship was observed between serum 25- hydroxy vitamin D with blood sugar, lipid profile, serum insulin level and HOMA-IR in obese women. Conclusion: No significant relationship was seen between serum level of 25- hydroxy vitamin D with anthropometric indices (except for body weight), serum levels of glucose, lipid profile and insulin resistance in the obese women.